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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2242 | Wnt-C59 | C59 | Wnt/beta-catenin , Porcupine |
Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity. | |||
T72322 | R 59-022 hydrochloride | DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride | 5-HT Receptor , PKC |
R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC).R 59-022 hydrochloride is a DGK inhibitor (IC50:2.8 µM) that inhibits the phosphorylation of OAG to OAPA.R... | |||
T2116 | AEE788 | NVP-AEE 788 | Apoptosis , EGFR , c-Fms , FLT , Bcr-Abl |
AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors. | |||
T16709 | R 59-022 | Diacylglycerol kinase inhibitor I,DKGI-I | Others |
R 59-022 is a 5-HTR antagonist and activates protein kinase C (PKC). R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits ... | |||
T76522 | HCV Core Protein (59-68) | ||
HCV Core Protein (59-68) is a peptide comprising residues 59-68 from the core protein of the Hepatitis C virus (HCV) [1]. | |||
T123989 | Solanapyrone C | ||
Solanapyrone C is a useful organic compound for research related to life sciences. The catalog number is T123989 and the CAS number is 88899-59-6. | |||
T70424 | EBI-907 | ||
EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907 displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). EBI-907 also... | |||
T35987 | CAY10563 | CAY10563 | |
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low m... | |||
T35988 | CAY10564 | ||
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low m... | |||
T38021 | Obafluorin | ||
Obafluorin is a β-lactone antibiotic that has been found in P. fluorescens.1 It is active against S. aureus, S. faecalis, K. pneumoniae, and P. vulgaris (MIC = 125 μg/ml for all). |1. Pu, Y., Lowe, C., Sailer, M., et al.... | |||
T21295 | BIX02189 | BIX 02189 | ERK , MEK |
BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM). | |||
T9470 | HPK1-IN-7 | MAPK | |
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM). | |||
T35712 | Debutyldronedarone hydrochloride | SR35021 hydrochloride | |
N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbut... | |||
T35779 | Oosporein | ||
Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectiv... |